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Applications of Pain Ease Topical Anesthetic Spray

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Give patients the comfort they deserve during minor procedures and injections

Whether you want to temporarily control the pain associated with minor procedures or you have patients who are worried about needle injections, Pain Ease® cold spray can be used in a number of applications to help improve patient comfort.

Gebauer's Pain Ease is a topical anesthetic skin refrigerant (vapocoolant) that begins working in just 4-10 seconds. Pain Ease is FDA-cleared to temporarily control the pain associated with needle procedures and minor surgical procedures.

Control pain for a variety of procedures, including:

Minor Surgical Procedures

  • Suturing or removing sutures
  • Lancing boils
  • Skin tag removal
  • Incision and drainage of small abscesses
  • Foreign body removal


Cold Spray for Injections

  • IV starts
  • Immunizations
  • Blood draws



Learn More About Pain Ease CTA

Frequently asked questions about applying Pain Ease

What types of procedures are appropriate to use Pain Ease?

Gebauer’s Pain Ease is a vapocoolant intended for topical application to skin, intact mucous membranes (oral cavity, nasal passageways and the lips) and minor open wounds. Pain Ease controls pain associated with injections (venipuncture, IV starts, cosmetic procedures), minor surgical procedures (such as lancing boils, incisions, drainage of small abscesses and sutures), and the temporary relief of minor sports injuries (sprains, bruising, cuts and abrasions).

When do I apply the Pain Ease?

Applying Pain Ease should be the last thing done before doing the procedure. Follow protocol when cleaning the area with an antiseptic, have all equipment ready for the procedure and then apply the Pain Ease immediately before doing the procedure.

How do I know the site is prepared for injection?

Spray Pain Ease for 4-10 seconds or until the skin begins to turn white, whichever comes first. Stop spraying after 10 seconds or if the skin blanches or begins to turn white. The skin is sufficiently cold and prepared for injection.

Can I use Pain Ease on an open wound?

Yes, Pain Ease is indicated for minor open wounds, intact mucous membranes (nasal passages, lips, and oral cavity) and skin. There is no systemic toxicity.

Can Pain Ease be used with laser equipment?

Yes, Pain Ease is non-flammable and can be used as a topical anesthetic prior to minor surgical procedures using laser equipment

Important Risk and Safety Information:

Consult your pediatrician when using on children 4 years old and younger. Do not use on large areas of damaged skin, puncture wounds, animal bites or serious wounds. Do not spray in eyes. Over spraying may cause frostbite. Freezing may alter skin pigmentation. Use caution when using the product on persons with poor circulation. Apply only to intact oral mucous membranes. Do not use on genital mucous membranes. The thawing process may be painful and freezing may lower resistance to infection and delay healing. If skin irritation develops, discontinue use. CAUTION: Federal law restricts this device to sale by or on the order of a licensed healthcare practitioner.

See how you can provide pain relief during a range of minor surgical procedures and needle injections

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Drawing blood no longer has to be an uncomfortable experience for patients.

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Pain Ease can reduce a patient's pain when removing foreign bodies.

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In just a few seconds, you can instantly control the pain and anxiety around starting an IV.

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Provide patient comfort during abscess incision and drainage.

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Temporarily control patients’ pain and reduce anxiety around suturing.

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Applying Pain Ease prior to injections can help provide patients with a more comfortable injection experience.

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Single patient option for Pain Ease instant topical anesthetic (1 oz).

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Help create a comfortable procedural experience with patients in 4-10 seconds.

With a wide variety of applications, you can provide improved comfort to more of your patients.

Learn more about how to temporarily control pain
and where to purchase Pain Ease below.